Shaunice Gamblin is a black female, 5'2" 115 pounds with brown eyes and brown and blue mohawk hairstyle.
Police say she ran away after an argument with her parents.
She was last seen wearing a black and red Old Navy hoodie, an unknown colored t shirt, blue shorts and white Converse sneakers.
Gamblin has reportedly been seen in the area of McCarthy Park and Amherst Street in Buffalo.
Anyone with information is asked to call Hamburg Police at 648-5111.